| 肝硬化患者血清SICAM-1、IL-6和TNF水平检测的临床意义 |
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| 引用本文： | 苏彩女,何浩明. 肝硬化患者血清SICAM-1、IL-6和TNF水平检测的临床意义[J]. 淮海医药, 2003, 21(4): 278-279 |
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| 作者姓名： | 苏彩女 何浩明 |
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| 作者单位： | 江苏省连云港市第一人民医院,检验科,222002 |
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| 摘 要： | 目的 探讨肝硬化患者 SICAM- 1、IL- 6和 TNF含量的变化。方法 用酶联免疫吸附法检测了 4 9例肝硬化患者血清中 SICAM- 1、IL - 6和 TNF含量 ,并以 35名正常人作对照。结果 肝硬化患者血清 SICAM- 1、IL- 6和 TNF含量均明显地高于正常人组 (P<0 .0 1) ,且与 AL T、TBil呈明显正相关。结论 检测肝硬化患者血清中 SICAM- 1、IL- 6和 TNF水平在一定程度上反映了机体的免疫功能状态、肝损害程度
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| 关 键 词： | 肝硬化 可溶性细胞间粘附分子-1 白细胞介素6 肿瘤坏死因子 |
| 文章编号： | 1008-7044(2003)04-0278-02 |
| 修稿时间： | 2002-08-29 |
Clinical significance of serum SICAM-1、IL-6 and TNF in patients with liver chirrosis |
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| SU Cai nui,HE Hao ming.. Clinical significance of serum SICAM-1、IL-6 and TNF in patients with liver chirrosis[J]. Journal of Huaihai Medicine, 2003, 21(4): 278-279 |
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| Authors: | SU Cai nui HE Hao ming. |
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| Abstract: | Objective The explore the changes of serum SICAM 1?IL 6 and TNF levels in patients with liver chirrosis.Methods Levels of serum SICAM 1,IL 6 and TNF were detected by enzyme linked immunosorbent assay(ELISA) in 49 cases of liver chirrosis and 35 normal controls.Results Serum levels of SICAM 1,IL 6 and TNF were obviously higher than those in normal controls( P <0.01).There were significamly positive correlation among serum levels of SICAM 1,IL 6,TNF,serum ALT and total bilirabin.Conclusion The serum levels of SICAM 1,IL 6 and TNF in patients with liver chirrosis reflect the immune function and degree of liver cells damage. |
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| Keywords: | Liver cirrhosis SICAM 1 Interleukin 6 Tumor necrosis factor |
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