左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床观察

目的探讨子宫腺肌症患者放置左炔诺孕酮宫内缓释系统(LNG-IUS,商品名:曼月乐)后的临床疗效及副反应。方法观察38例子宫腺肌症的患者,放置LNG-IUS前、1个月、3个月、6个月月经情况、痛经程度、子宫体积内膜变化。结果放置LNG-IUS后,痛经显著缓解,疼痛评分从75±15降到22±7(P<0.05)。经量评分置环前、置环后1个月、3个月、6个月分别为(197±65)、(53±22)(、42±13)、(25±13)。6个月内子宫内膜明显变薄,差异显著。子宫体积在置环前后没有明显的变化。有4例患者出现卵巢生理性囊肿。结论LNG-IUS是治疗子宫腺肌症的一种较为有效且安全的方法。

Clinical study of levonorgestrel-releasing intrauterine system in the treatment of adenomgosis

Objective To investigate the clinical efficacy of levonorgestrel-releasing intrauterine system(LNG-IUS) in the treatment of adenomyosis.Methods Thirty eight patients with adenomyosis were followed up in 0,1,3,6 months after treating with LNG-IUS.The menstrual blood volume,dysmenorrheal,size of ulteri and endometrial thickness were observed and evaluated.Results After inserting LNG-IUS,dysmenorrhea was obviously alleviated,and the dysmenorrheal scores decreased to(22±7) from(75±15)(P<0.05).The menstrual blood volume by PBAC were(197±65),(53±22),(42±13) and(25±13) in 0,1,3,6 months after the insertion.Endometrial thickness reduced significantly in 6 months,and the size of uteri didn't change significantly.Conclusion LIG-IUS is an effective and safe therapy for adenomyosis.