| 功率谱熵在局灶性缺血性脑损伤无创检测中的应用 |
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| 引用本文： | 吴浩江,张辉,郑崇勋,孔金生. 功率谱熵在局灶性缺血性脑损伤无创检测中的应用[J]. 生物医学工程学杂志, 2003, 20(2): 229-232 |
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| 作者姓名： | 吴浩江 张辉 郑崇勋 孔金生 |
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| 作者单位： | 西安交通大学,生命科学与技术学院生物医学工程研究所,西安,710049 |
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| 基金项目： | 国家自然科学基金资助项目 (3 9970 2 0 4) |
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| 摘 要： | 为了对局灶性缺血脑损伤的程度进行无创诊断，并对损伤区域进行定位，用SD(Sparague—dawley)实验大鼠建立了一个局灶性缺血脑损伤的动物实验模型，采得缺血前到缺血30min时的缺血区域与正常区域的EEG(Electroencephalogram)信号，并采用功率谱熵对EEG信号进行了分析。结果发现局灶性脑缺血导致EEG信号的功率谱熵发生了明显的变化。缺血侧的EEG信号的功率谱熵在缺血15min时已经明显低于缺血前的正常值，在整个缺血过程中缺血侧的EEG信号的功率谱熵小于正常区域的功率谱熵。这表明EEG信号的功率谱熵是一种很好的表征脑缺血损伤的参数，具有计算简便、有效的优点。
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| 关 键 词： | 功率谱熵 局灶性缺血 脑损伤 无创检测 动物模型 脑电图 |
Application of Power Spectral Entropy to the Noninvasive Detection of Focal Ischemic Cerebral Injury |
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| Wu Haojiang Zhang Hui Zheng Chongxun Kong Jinsheng. Application of Power Spectral Entropy to the Noninvasive Detection of Focal Ischemic Cerebral Injury[J]. Journal of biomedical engineering, 2003, 20(2): 229-232 |
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| Authors: | Wu Haojiang Zhang Hui Zheng Chongxun Kong Jinsheng |
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| Affiliation: | Institute of Biomedical Engineering, School of Life Sciences and Techniques, Xi'an Jiaotong University, Xi'an 710049. |
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| Abstract: | A model of SD rat focal ischemic cerebral injury is presented for use in noninvasively detecting both the extent and the location of focal ischemic cerebral injury. EEG signals of ischemic region and normal region are recorded from the moment before ischemia to 30 minutes after ischemia. Then the Power Spectral Entropy(PSE) analysis of EEG is performed. Results show that the PSE of EEG signals changes greatly as a result of focal ischemic cerebral injury. The PSE of EEG signal of ischemic region is less than that before ischemia as the ischemia lasts 15 minutes.The PSE of EEG signals of ischemic region is much less than that of normal region. These indicate that the power spectral entropy of EEG signal is a good index of focal ischemic cerebral injury and the method of power spectral entropy analysis is simple and effective. |
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| Keywords: | Power spectral entropy(PSE) Focal ischemia Cerebral injury Electroencephalogram (EEG) |
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