| 稳心颗粒联合美托洛尔治疗风湿性心脏病换瓣术后频发性室性期前收缩 |
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| 引用本文： | 韦旭波,朱中权.稳心颗粒联合美托洛尔治疗风湿性心脏病换瓣术后频发性室性期前收缩[J].中西医结合心脑血管病杂志,2011,9(9):1063-1064. |
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| 作者姓名： | 韦旭波 朱中权 |
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| 作者单位： | 中国人民解放军第一八一医院心脏中心,541002。 |
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| 摘 要： | 目的评价美托洛尔联合稳心颗粒治疗风湿性心脏病换瓣术后频发室性期前收缩的临床疗效及安全性。方法将风湿性心脏病换瓣术后频发室性期前收缩患者68例,随机分为两组。两组患者均常规口服美托洛尔,治疗组加服稳心颗粒,每次9g,每日3次,2周为1个疗程。观察两组患者临床症状、24h动态心电图、华法林用量、凝血酶原时间(PT)及国际化标准比值(INR)变化。结果治疗1个疗程后,两组症状及室性期前收缩明显减少。治疗组临床疗效总有效率91.18%,明显高于对照组79.41%(P<0.05),24h室性期前收缩减少总有效率88.23%,明显高于对照组82.35%(P<0.05),且未见严重不良反应。两组治疗前后华法林用量、PT及INR无明显差异(P>0.05)。结论稳心颗粒联合美托洛尔治疗风湿性心脏病术后室性频发早搏疗效明显,优于单用美托洛尔,且对华法林抗凝治疗无明显影响。
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| 关 键 词： | 稳心颗粒 美托洛尔 室性期前收缩 风湿性心脏病 |
Wenxin Granule Combined with Metoprolol for Treatment of Frequent Ventricular Premature Contractions in Rheumatic Heart Disease after Valve Replacement Surgery |
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| Wei Xubo,Zhu Zhongquan.Wenxin Granule Combined with Metoprolol for Treatment of Frequent Ventricular Premature Contractions in Rheumatic Heart Disease after Valve Replacement Surgery[J].Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease,2011,9(9):1063-1064. |
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| Authors: | Wei Xubo Zhu Zhongquan |
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| Institution: | Wei Xubo,Zhu Zhongquan Cardiac Center,The 181 Hospital of PLA(Guilin 541002) |
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| Abstract: | Objective To observe the efficacy and safety of Wenxin granule combined with metoprolol for treatment of frequent ventricular premature contractions in patients(pts) with rheumatic heart disease after valve replacement surgery.Methods Sixty-eight pts with frequent ventricular premature contractions and rheumatic heart disease after valve replacement surgery were randomly divided into two groups:Control group treated by metoprolol and treatment group treated by Wenxin granule and metoprolol for 2 weeks.The t... |
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| Keywords: | Wenxin granule metoprolol ventricular premature contractions rheumatic heart disease |
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