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Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency. |
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| Authors: | Nima Parvaneh Shohreh Shahmahmoudi Hamideh Tabatabai Mohsen Zahraei Taha Mousavi Abdol-Reza Esteghamati Mohammad M Gooya Setareh Mamishi Rakhshandeh Nategh Olen M Kew |
| Affiliation: | Department of Pediatrics, Infectious Disease Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. |
| Abstract: | Vaccine-associated paralytic poliomyelitis (VAPP) is a rare complication of oral polio vaccine. We describe a fatal case of VAPP in an 8-month-old boy with Major Histocompatibility Class II deficiency. The isolated poliovirus was a Sabin type 2-type 1 recombinant that showed 1.4% VP1 divergence from Sabin type 2. |
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