女性非小细胞肺癌患者预后影响因素分析

目的 探讨女性非小细胞肺癌预后影响因素。方法 回顾性分析326例女性非小细胞肺癌患 者的临床资料，随访生存期为2006年12月至2013年1月。采用Kaplan-Meier绘制生存曲线，Cox比例风 险回归模型进行单因素和多因素分析。结果 女性肺腺癌、肺鳞癌的5年生存率分别为28.9%和19.3% （P＜0.0001）；N2、N1、N0的5年生存率分别为4.1%、23.8%和66.1%（P＜0.0001）；治疗前有、无 胸腔积液者的5年生存率分别为6.8%和38.4%（P＜0.0001）。结论 病理类型、N分期、治疗前胸腔 积液是女性非小细胞肺癌患者的独立预后因素。

Prognostic Factors for Female Non-small Cell Lung Cancer Patients

Objective To explore the prognostic factors for female non-small cell lung cancer (NSCLC) patients. Methods Clinical data of 326 cases of female NSCLC patients were retrospectively analyzed. Follow-up survival period was from December 2006 to January 2013. Kaplan-Meier was applied to plot survival curves. Univariate and multivariate effects were measured by Cox proportional hazard regression. Results Five-year survival rates of female adenocarcinoma and squamous carcinoma patients were 28.9% and 19.3%(P＜0.0001), respectively. Five-year survival rates of N2, N1, N0 were 4.1%, 23.8% and 66.1%(P ＜0.0001) , respectively. Five-year survival rates of patients with or without pleural effusion before treatment were 6.8% and 38.4% (P＜0.0001), respectively. Conclusion Histological type, N stage and pleural effusion before treatment are the independent prognostic factors for female NSCLC patients.