| 2型糖尿病载脂蛋白ApoA1、ApoB100检测的临床研究 |
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| 引用本文： | 袁美玲,倪红兵.2型糖尿病载脂蛋白ApoA1、ApoB100检测的临床研究[J].南通医学院学报,2009,29(6). |
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| 作者姓名： | 袁美玲 倪红兵 |
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| 作者单位： | 1. 南通大学附属医院,耳鼻咽喉科实验室,南通,226001
2. 南通大学附属医院,检验医学中心,南通,226001 |
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| 摘 要： | 目的:探讨人血清血脂和载脂蛋白ApoA1、ApoB100的水平及ApoA1/ApoB100比值在2型糖尿病并发心血管疾病的意义。方法:选取2型糖尿病患者55例,根据有无并发症分为4组(无并发症组,1种并发症组,2种并发症组,3种并发症组)。同期选取健康人47例对照组。全自动生化分析仪测定各组血清TG、TC、LDL-C、HDL-C、ApoA1、ApoB100水平,并计算ApoA1/ApoB100比值。结果:2型糖尿病组与对照组相比TG、TC、LDL-C、ApoB100水平明显升高(P<0.01),HDL-C、ApoA1/ApoB100比值明显下降(P<0.05),ApoA1水平无明显下降(P>0.05)。2型糖尿病并发心血管病变各组与无并发症组相比,TG、TC、HDL-C、ApoA1水平改变不明显(P>0.05),LDL-C和ApoB100水平明显升高,ApoA1/ApoB100比值显著降低(P<0.05)。结论:定期检查ApoB100和ApoA1/ApoB100,为糖尿病患者预测是否并发心血管病变风险有重要意义。
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| 关 键 词： | 2型糖尿病 载脂蛋白 ApoA1/ApoB100 心血管疾病 |
The clinical study of serum lipids in patients with type 2 diabetes mellitus |
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| Institution: | YUAN Meiling1; NI Hongbing2(1Department of Otorhinolaryngology; 2The Center of Laboratory Medicine; Affiliated Hospital of Nantong University; Nantong 226001); |
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| Abstract: | Objective:To study the application of lipoprotein,apolipoprotein ApoA1,ApoB100 level and the ratio of ApoA1/ApoB100 in type 2 diabetes mellitus patients associated with cardiovascular disease.Methods:Fifty-five cases of type 2 diabetes mellitus patients were enrolled in this study which were divided into four groups(no complication,one type of complication,two types of complications,three types of complications).Take 47 cases healthy volunteers as control group.All groups of TG,TC,LDL-C,HDL-C,ApoA1,ApoB100 ... |
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| Keywords: | ApoA1/ApoB100 |
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