| 羊水细胞培养及染色体核型分析在产前诊断中的应用 |
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| 引用本文： | 胡美红,刘雨生,何国平,陈玲,周桂香,宋雅娴,童先宏,骆丽华.羊水细胞培养及染色体核型分析在产前诊断中的应用[J].临床输血与检验,2011,13(1):23-25. |
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| 作者姓名： | 胡美红 刘雨生 何国平 陈玲 周桂香 宋雅娴 童先宏 骆丽华 |
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| 作者单位： | 1. 安徽医科大学附属省立医院生殖医学中心,合肥,230001
2. 安徽医科大学附属省立医院妇产科 |
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| 摘 要： | 目的 探讨羊水细胞培养及染色体核型分析在产前诊断中的应用价值.方法 从中孕期妇女羊膜腔穿刺获取羊水,细胞培养后分析染色体核型,进行产前诊断.结果 17例产前诊断患者羊水细胞培养及制片成功率均为100%,共检出异常染色体核型3例,检出率为17.65%,其中21三体2例(11.76%),胎儿2N/4N嵌合体1例(5.88%...
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| 关 键 词： | 产前诊断 羊水细胞 染色体核型分析 唐氏综合征 |
The Value of Culturing Amniotic Fluid Cell and Chromosome Analysis in Prenatal Diagnosis |
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| HU Mei-hong,LIU Yu-sheng,HE Guo-ping,et al..The Value of Culturing Amniotic Fluid Cell and Chromosome Analysis in Prenatal Diagnosis[J].Journal of Clinical Transfusion and Laboratory Medicine,2011,13(1):23-25. |
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| Authors: | HU Mei-hong LIU Yu-sheng HE Guo-ping |
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| Institution: | HU Mei-hong,LIU Yu-sheng,HE Guo-ping,et al.Reproductive Centre of Anhui Provincial Hospital,Anhui Medical University,Hefei 230001 |
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| Abstract: | Objective To evaluate the feasibility and reliability of using cultured amniotic fluid cells and chromosome analysis for prenatal diagnosis.Methods Amniotic fluid cells were cultured for chromosome analysis.Results 3 cases of chromosome abnormalities were detected in 17 cases of amniotic fluid cells and the detection rate of chromosome abnormalities was 17.65%.Among the chromosome abnormalities 2 cases were Trisomy 21(11.76%) and the other cases were chromosome mosaicism 2N/4N(5.88%).Conclusion Culturing am... |
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| Keywords: | Prenatal diagnosis Amniotic fluid cell Chromosome analysis Down syndrome |
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