| 淫羊藿对兔主动脉条收缩反应的影响 |
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| 引用本文： | 曾青. 淫羊藿对兔主动脉条收缩反应的影响[J]. 赣南医学院学报, 1990, 10(4): 218-220 |
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| 作者姓名： | 曾青 |
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| 作者单位： | 赣南医学院药理学教研室 |
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| 摘 要： | 淫羊藿水取液使NE和KCl收缩兔主动脉条的量—效反应曲线均右移,并抑制最大效应。明显减弱NE收缩反应中内Ca~(2+)释放依赖性部分,对NE所引起的依赖细胞外Ca~(2+)的收缩比前者更强。提示淫羊藿水提取液可抑制细胞膜上电位依赖性Ca~(2+)通道,同时对受体控制性Ca~(2+)通道抑制作用更强。
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| 关 键 词： | 淫羊藿 血管收缩 药效 兔 |
Effect of herba epimedii on contraction ofrabbit aortic strips |
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| Zeng Jing. Effect of herba epimedii on contraction ofrabbit aortic strips[J]. Journal of Gannan Medical College, 1990, 10(4): 218-220 |
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| Authors: | Zeng Jing |
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| Affiliation: | Department of Pharmacology |
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| Abstract: | Herba epimedii ( HE ) nonparellelly shifted norepinephrine ( NE ) or potassium chloride ( KC1 ) dose -response to the right, and restrained the maximal response. HE obviously weakened the intracellular calcium - dependent component and much more strongly weakened the extracellular calcium - dependent component. The results showed that HE could inhibit potential -dependent calcium channel and receptor operated channel. |
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| Keywords: | Herba epimedii/pharmacodynamics Aorta Phoracic/drug effects Vasoconstriction/drug effects Dose - Response Reationship drug Rabbits |
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