| 抗精子抗体相关靶抗原的研究进展 |
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| 引用本文： | 陈德宇,黄宇烽. 抗精子抗体相关靶抗原的研究进展[J]. 中华男科学杂志, 2004, 10(6): 458-460,464 |
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| 作者姓名： | 陈德宇 黄宇烽 |
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| 作者单位： | 南京军区南京总医院生殖遗传研究室,江苏,南京,210002 |
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| 基金项目： | 江苏省科技厅高新技术基金 |
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| 摘 要： | 抗精子抗体能导致免疫性不育 ,对抗精子抗体靶抗原的深入研究有助于揭示抗精子抗体与不育的因果关系。本文综述了近年来陆续发现的 6种重要的抗精子抗体靶抗原的结构和功能 ,为进一步探讨抗精子抗体与不育的因果关系以及筛选免疫避孕疫苗奠定基础。
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| 关 键 词： | 抗精子抗体 靶抗原 不育 |
| 文章编号： | 1009-3591(2004)06-0458-04 |
| 修稿时间： | 2004-02-13 |
Advances in Research on the Target Antigens of Antisperm Antibodies |
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| Chen Deyu,Huang Yufeng Laboratory of Reproduction , Genetics,Nanjing General Hospital of Nanjing Command,PLA,Nanjing,Jiangsu ,China. Advances in Research on the Target Antigens of Antisperm Antibodies[J]. National journal of andrology, 2004, 10(6): 458-460,464 |
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| Authors: | Chen Deyu Huang Yufeng Laboratory of Reproduction & Genetics Nanjing General Hospital of Nanjing Command PLA Nanjing Jiangsu China |
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| Affiliation: | Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China. |
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| Abstract: | Antisperm antibodies can lead to immunological infertility. Further research on the target antigens of antisperm antibodies may help to discover the causal relationship of antisperm antibodies to infertility. This paper summarizes the structure and function of the six target antigens of antisperm antibodies found recently,so as to discover the causal relationship of the antibodies to infertility and provide a basis for screening a vaccine for immunological contraception. |
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| Keywords: | antisperm antibody target antigen infertility |
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