215例早期胃癌淋巴结转移的危险因素分析

  目的   探讨早期胃癌淋巴结转移的危险因素。   方法   回顾性分析2005年1月至2010年12月安徽医科大学附属省立医院普外科收治的215例早期胃癌患者的临床病理资料, 并研究早期胃癌淋巴结转移与临床病理因素的关系。   结果   215例患者中淋巴结转移者36例, 单因素分析显示: 肿瘤最大直径(P=0.022)、浸润深度(P=0.003)、Hp感染情况(P=0.004)均与早期胃癌淋巴结转移有关。Logistic多因素回归分析显示: 肿瘤的浸润深度与早期胃癌淋巴结转移有关(P=0.002)。   结论   肿瘤的浸润深度是影响早期胃癌淋巴结转移的独立危险因素。 

Associated risk factors for lymph node metastasis in early gastric cancer

  Objective   This study was designed to investigate the risk factors for lymph node metastasis in early gastric cancer.   Methods   We retrospectively analyzed the clinicopathological data of 215 patients with early gastric cancer treated at the Anhui Province Hospital from January 2005 to December 2010.The relationship between lymph node metastasis and cliniopathological factors was evaluated by univariate and multivariable logistic regression analyses.   Results   Univariate analysis showed that tumor size(P=0.001), depth of invasion(P=0.000), and Helicobacter pylori infection(P=0.000) were associated with lymph node metastasis.Multivariable logistic regression analysis revealed that the depth of invasion was considered a significant risk factor(P < 0.05).   Conclusion   The depth of invasion is the risk factor for lymph node metastasis in early gastric cancer.