Cytokines and growth factors involved in peritoneal fibrosis of peritoneal dialysis patients |
| |
Authors: | Oh K-H Margetts P J |
| |
Affiliation: | Department of Medicine, McMaster University, Division of Nephrology, St Joseph's Hospital, 50 Charlton Ave E, Hamilton, Ontario, Canada L8P 4A6. |
| |
Abstract: | Peritoneal fibrosis is initiated by exposure of peritoneal tissues to numerous harmful agents encountered during peritoneal dialysis. These agents interact with cells within the peritoneum to induce growth factors and cytokines that are important in the initiation, progression and maintenance of fibrosis. Some of the mediators implicated in the pathogenesis of peritoneal fibrosis include transforming growth factor (TGF) beta, connective tissue growth factor (CTGF), fibroblast growth factors (FGF), and platelet derived growth factor (PDGF). |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|