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细菌内毒素法检查碳酸氢钠注射液热原的研究
引用本文:王立军,周学琴,张耀东.细菌内毒素法检查碳酸氢钠注射液热原的研究[J].中国药业,2004,13(1):46-47.
作者姓名:王立军  周学琴  张耀东
作者单位:北京大学深圳医院,广东,深圳,518036
摘    要:目的:研究用细菌内毒素法检查碳酸氢钠注射液的热原.方法:应用鲎试剂检查碳酸氢钠注射液中的热原,考察了碳酸氢钠注射液对细菌内毒素检查法的干扰行为.结果:碳酸氢钠注射液稀释2.5倍,对细菌内毒素检查法无干扰作用.结论:选用鲎试剂,细菌内毒素检查可代替碳酸氢钠注射液热原检查法.

关 键 词:碳酸氢钠注射液  鲎试剂  细菌内毒素检查法
文章编号:1006-4931(2004)01-0046-01
修稿时间:2003年9月7日

Study of Bacterial Endotoxin Test in Sodium Bicarbonate Injection
Wang Lijun,Zhou Xueqin,Zhang Yaodong.Study of Bacterial Endotoxin Test in Sodium Bicarbonate Injection[J].China Pharmaceuticals,2004,13(1):46-47.
Authors:Wang Lijun  Zhou Xueqin  Zhang Yaodong
Abstract:Objective: To investigate the bacterial endoloxin test in sodium bicarbonate injection. Methods: Use bacteria enclotoxin test to detect pyrogen in sodium bicarbonate injection, and the interference of sodium bicarbonate injection to the process of bacterial endoloxin test was studied. Results: Sodium bicarbonate injection has no interference to the bacterial endotoxin test, when it is diluted for 2. 5 times. Conclusion: The bacterial endoloxin test could be used for pyrogen test of sodium bicarbonate injection.
Keywords:Sodium Bicarbonate Injection  Limulus Amebocyte Lysute  Bacterial Endotoxin
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