间苯三酚在产程活跃期应用的临床分析

目的观察第一产程活跃期中使用间苯三酚促进宫颈扩张及加速产程进展的作用。方法选择足月妊娠单胎头位初产妇，于第一产程活跃期，宫口扩张3～4cm，伴宫颈水肿、坚韧、宫口扩张延缓者80例，随机分为治疗组和对照组各40例。采用单盲法：间苯三酚组，静脉推注间苯三酚80mg，地西泮组静脉缓慢推注地西泮10mg，观察两组宫颈扩张速度、产程进展、新生儿Apgar评分、产后出血量。结果①间苯三酚组第一产程活跃期平均时间为（3．41±0．49）h，地西泮组平均时间为（4．20±0．31）h，差异有统计学意义（P〈0．05）；②两组新生儿Apgar评分及产后出血量无明显差异（P〉0．05）。结论第一产程活跃期应用间苯三酚可加速宫颈扩张、加速产程进展，而且对母儿有较高的安全性。

Clinical analysis of Phloroglucinol on course of active phase

Objective To observe the effects of Phloroglucinol on improving dilatation of cervix and promoting the progression of labor. Methods A total of 80 normal primiparas with cervical edema were ran- domized into study group （Phloroglucinol group, 80 mg Phloroglucinol by intravenous injection, n = 40 ） and control group（diazepam group, 10 mg diazepam by intravenous injection, n =40）. Results （1）The mean time of the active phase in Phloroglucinol group was （ 3.41±0. 49 ） hour, The mean time of the active phase in diazepam group was（4. 20±0. 31 ）hour, respectively （P 〈 0. 05 ）. （2）There was statistically significant different in Apgar score of neonatal and pastpartum hemorrhage between the two groups, either（ P 〉 0. 05 ）. Conclusion Phloroglucinol can use in active phase to accelerate cervical dilatation and to short the labor, without adverse effect on laboring women and fetuses.