三阴乳腺癌磁共振成像研究

三阴性乳腺癌(TNBC)具有特殊的生物学和临床病理学特征。由于侵袭性强,缺乏有效的靶向治疗和内分泌治疗,预后差。目前磁共振成像是诊断乳腺癌最准确的影像学检查方法,可协助诊断和预后评估。三阴性乳腺癌典型MRI表现为单一病灶,呈肿块型,形态不规则,边缘光滑,在T2WI上病变中心呈高信号。进一步的工作是研究磁共振成像的临床应用,动态增强磁共振成像(DCE-MRI)、DWI、MR波谱(MRS)等。

Research in magnetic resonance imaging of triple-negative breast cancer

Triple-negative breast cancer (TNBC), which characterized by distinct biological and clinical pathological features, has a worse prognosis because of the lack of effective therapeutic targets. Breast MR is the most accurate imaging modality for diagnosis of breast cancer currently. MR imaging recognition could assist in diagnosis, pretreatment planning and prognosis evaluation of TNBC. MR findings of a larger solitary lesion, mass with smooth mass margin, high signal intensity on T2-weighted images and rim enhancement are typical MRI features associated with TNBC. Further work is necessary about the clinical application of dynamic contrast-enhanced MR imaging (DCE-MRI), DWI and MRS.