中国老年男性骨质疏松症影响因素的Meta分析

目的 通过Meta分析明确中国老年男性罹患骨质疏松(osteoporosis,OP)的主要影响因素.方法 使用计算机检索中国知网、万方数据库、维普网、PubMed、Web of Science、Embase数据库(自建库以来至2020年1月),并使用NOS进行文献质量评价,使用RevMan 5.3进行Meta分析.结果...

Meta-analysis of the influencing factors of osteoporosis in Chinese elderly men

Objective To identify the main influencing factors of OP in the elderly men in China through Meta-analysis.Methods The literatures of CNKI,Wanfang Database,VIP Network,PubMed,Web of Science,Embase Database(from inception to January 2020)were screened.The quality was evaluated according to NOS.Meta-analysis was performed using a RevMan5.3 software.Results A total of 21 reference were included,18 influencing factors were extracted.Meta-analysis showed that age,height,weight,BMI,BMD,education level,fracture history,serum calcium level,smoking,sunlight exposure,exercise,drinking tea,calcium supplement history,drinking milk and vitamin D supplementation history were associated with OP,and the differences were statistically significant(P<0.05).There were no statistically significant(P>0.05)in drinking,25-(OH)D and serum phosphorus level.Conclusion Body weight,BMI,BMD,milk drinking,calcium supplement,vitamin D supplement,serum calcium level,tea drinking,exercise,sunlight exposure and cultural level were protective factors;age,loss of height,smoking and fracture history were the risk factors;The factors of drinking,25-(OH)D and serum phosphorus level need to be further vertified.