| 可诱导共刺激分子及其配体与系统性红斑狼疮的研究进展 |
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| 引用本文： | 罗 娜,李亚妤. 可诱导共刺激分子及其配体与系统性红斑狼疮的研究进展[J]. 浙江中西医结合杂志, 2021, 31(2) |
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| 作者姓名： | 罗 娜 李亚妤 |
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| 作者单位： | 浙江中医药大学附属广兴医院,浙江中医药大学附属广兴医院 |
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| 摘 要： | 可诱导共刺激分子(ICOS)及其配体可诱导共刺激分子配体(ICOSL)是CD28/B7家族第三个成员,在系统性红斑狼疮的发生发展中发挥重要作用。近些年,ICOS/ICOSL在SLE的治疗方面的研究逐年深入,为临床SLE治疗提供了新思路。本文主要就ICOS/ICOSL与SLE关系进行概述。
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| 关 键 词： | 可诱导共刺激分子 可诱导共刺激分子配体 系统性红斑狼疮 狼疮性肾炎 |
| 收稿时间： | 2020-07-12 |
| 修稿时间： | 2020-09-13 |
Research progress on inducible costimulatory molecules and their ligands and systemic lupus erythematosusLuo Na Li Yayu |
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| Abstract: | Inducible Costimulatory Molecule (ICOS) and its ligand Inducible Costimulatory Molecule Ligand (ICOSL) is the third member of the CD28/B7 family and plays an important role in the development of systemic lupus erythematosus. In recent years, ICOS/ICOSL"s research on the treatment of SLE has been deepened year by year, providing new ideas for clinical SLE treatment. This article mainly summarizes the relationship between ICOS/ICOSL and SLE. |
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| Keywords: | Inducible costimulatory molecule inducible costimulatory molecular ligands systemic lupus erythematosus lupus nephritis |
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