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哥兰叶中黄酮类化学成分的研究
引用本文:冯卫生,郝志友,郑晓珂,匡海学. 哥兰叶中黄酮类化学成分的研究[J]. 中国药学杂志, 2008, 43(8): 573-575
作者姓名:冯卫生  郝志友  郑晓珂  匡海学
作者单位:1. 河南中医学院,郑州,450008
2. 黑龙江中医药大学,哈尔滨,150040
基金项目:教育部科学技术研究重点项目
摘    要: 目的研究哥兰叶(Celastrus gemmatus Loes.)中的化学成分。方法用色谱方法并结合重结晶等方法进行分离,用波谱学方法鉴定其化合物结构。结果分离得到5个化合物,分别为5,4′-二羟基-3′-甲氧基黄酮-7-O-β-D-半乳糖醛酸苷(1),槲皮素-3-O-新橙皮糖苷(2),木犀草素(3),芹菜素-8-C-β-D吡喃葡萄糖苷(4),山柰酚-3,7-二-O-β-D-吡喃葡萄糖苷(5)。结论化合物1为新化合物,其他均为首次从本植物中分得。

关 键 词:哥兰叶  黄酮类化合物  结构鉴定  5  4′-二羟基-3′-甲氧基黄酮-7-O-β-D-半乳糖醛酸苷
文章编号:1001-2494(2008)08-0573-03
收稿时间:2007-05-02;
修稿时间:2007-05-02

Study on Flavonoids from the Leaves of Celastrus gemmatus Loes.
FENG Wei-sheng,HAO Zhi-you,ZHENG Xiao-ke,KUANG Hai-xue. Study on Flavonoids from the Leaves of Celastrus gemmatus Loes.[J]. Chinese Pharmaceutical Journal, 2008, 43(8): 573-575
Authors:FENG Wei-sheng  HAO Zhi-you  ZHENG Xiao-ke  KUANG Hai-xue
Affiliation:1. Henan College of Traditional Chinese Medicine,Zhengzhou 450008,China; 2. Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China
Abstract:OBJECTIVE To study the chemical constituents of flavonoids from the leaves of Celastrus gemmatus Loes.METHODS The constituents were isolated by methods of column chromatography,preparative HPLC and recrystallization,and then their structures were identified by spectroscopic methods.RESULTS Five compounds were obtained and identified as 5,4'-dihydroxy-3'-methoxyflavone-7-O-β-D-galacturonide(1),quercetin-3-O-neohesperidoside(2),luteolin(3),apigenin-8-C-β-D-glucopyranoside(4),kaempferol-3,7-di-O-β-D-glucopyranoside(5),respectively.CONCLUSION Commpound 1 was a new compound,the others were isolated from this plant for the first time.
Keywords:Celastrus gemmatus Loes.')"   href="  #"  >Celastrus gemmatus Loes.  flavonoids  structure identification  5  O-β-D-galacturonide ')"   href="  #"  > 4'-dihydroxy-3'-methoxyflavone-7-O-β-D-galacturonide
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