血清高敏C反应蛋白水平与心肌梗死关系的研究

目的：探讨血清高敏C反应蛋白（hs—CRP）水平与心肌梗死病情及预后的关系。方法：测定40例急性心肌梗死患者（观察组）入院时血清hs—CRP含量，同时选取同期40例健康体检人员（对照组）血清hs—CRP含量进行对照。并将血清hs—CRP水平与心肌肌钙蛋白（cTnI）、心肌同功酶（CK—Mb）水平进行相关性分析。结果：心肌梗死患者血清hs—CRP含量明显高于健康对照组（P〈0．01）。患者血清hs—CRP水平与入院时cTnI、CK—Mb呈显著正相关（P〈0．05）。心肌梗死灶越大，血清hs—CRP水平越高，心肌功能缺损程度越重。结论：血清hs—CRP水平是临床评价心肌梗死严重程度和预后的一个重要生物学指标。

Relationship between serum high sensitivity C-eactive protein level and myocardial infarction

Objective：To investigate the relationship between serum high sensitivity C-reactive protein （hs-CRP） level and the severity and prognosis in myocardial infarction. Methods：Serum hs-CRP level of forty patients with acute myocardial infarction were evaluated. Serum hs-CRP levels were measured in eighty normal people as control group. Results：The levels of hs-CRP in myocardial infaretion patients were markedly higher than that in control group （P〈0.05）.Furthermore, the mean serum hs-CRP levels were higher in the patients with bigger volume of myocardial infarction.Serum hs-CRP level was correlated significantly with cTnI and CK-Mb. Conclusion： The serum hs-CRP can be a sensitive index in the patients with myocardial infarction.