双水平正压无创机械通气治疗重症支气管哮喘的临床观察

目的探讨双水平正压元创机械通气治疗重症支气管哮喘的临床效果。方法将69例重症支气管哮喘患者随机分为观察组35例和对照组34例，对照组采用传统治疗方法，观察组采用无创机械通气模式和基础治疗。比较两组实施治疗前、治疗3d后患者的临床症状、体征及动脉血气指标（PaCO2、PaO2、saO2）变化。结果观察组临床症状的改善情况、需要气管插管的病例数和血气分析结果（PaCO2、PaO2、SaO2）明显优于对照组（P〈0．05）。结论重症支气管哮喘患者在常规治疗的基础上加用无创机械通气治疗，可有效改善患者的临床症状，安全有效，减少患者痛苦。

Observation of ehlnlcal efficacy of BiPAP non-invasive mechanical ventilation in the salvage of patients withsevere asthma

Objective To evaluate the clinical efficacy of BiPAP non-invasive mechanical ventilation in the treatment of patients with severe asthma. Methods Sixty-nine patients with severe asthma were divided into the observation group （35 patients） and control group （34 patients）. The control group were give routine treatment, the observation group were treated with BiPAP ventilation in addition to the routine treatment. The changes of clinical symptoms and arterial blood gas （ PaCO2, PaO2 and SaO2 ） before and 3 days after the treatment were compared. Resuits The observation group showed significantly improvement in PaCO2, PaO2 and SaO2 and need tracheal intubation cases and clinical situation compared with control group （ P 〈 0. 05 ）. Conclusion Using non-invasive ventilation based on routine treatment can improved the clinical manifestation, which is efficient, safe and less painful.