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数字影像学检查在大鼠肺癌模型中的应用
引用本文:徐忠建,周素军,鲁植艳. 数字影像学检查在大鼠肺癌模型中的应用[J]. 医学新知杂志, 2005, 15(4): 35-36,F0003
作者姓名:徐忠建  周素军  鲁植艳
作者单位:武汉大学中南医院放射科,武汉,430071
基金项目:湖北省科技厅“十五”攻关计划资助,课题号20001P1804
摘    要:目的探讨数字影像在大鼠肺癌模型中的应用。方法将140只经左肺叶灌注含敛癌质碘油的大鼠随机分为2组:实验组84只,用philips V5000 DSA机摄胸部照片;对照组56只,使用岛津UD 150L-30E X光机摄胸片。每组均于灌注后1、14、30~42 d检查肺部3次,共计摄片420次。每组从制模成功的大鼠中随机抽取30只,最后一次摄片时测量病变大小,并与病理结果对照。结果实验组大鼠肺部图像中,甲、乙、丙级片分别为89.3%、10.7%、0.0%;对照组分别为71.4%、23.2%、5.4%。病变定位正确率两者均为100%,病变大小测量误差率:实验组0级56.6%、I级40%;对照组0级33.3%、I级36.7%。结论数字影像检查大鼠肺癌比常规X线摄片清晰、准确,可用于肺癌的检查和辅助诊断。

关 键 词:肺癌  大鼠  数字化像影
收稿时间:2004-12-27
修稿时间:2004-12-27

Digital Image Analysis in Lung Cancer Model of Rats
Xu Zhongjian,Zhou Sujun,Lu zhiyan. Digital Image Analysis in Lung Cancer Model of Rats[J]. Journal of New Medicine, 2005, 15(4): 35-36,F0003
Authors:Xu Zhongjian  Zhou Sujun  Lu zhiyan
Affiliation:Department of radiology, Zhongnan Hospital,Wuhan University Wuhan 430071
Abstract:Objective To evaluate the implication of digital image in lung cancer model of rats and the quality of radiology on digital image. Methods 140 Wistar rats were perfused with tumor-inducilble iodinated-oil in left pulmonary by digital image and quality of the photo was compared with that of the other 56 rats'conven-tional radiology. Results The graphic quality in digital image group was better than that of conventional radiology which the rats of A,Band C grade graphic quality was 39.3%, 10.7%and 0% respectively vs 71.4%,23.2%and 5.4% in conventional group. Conclusion digital image is superior to the conventional radiology in graphic quality for evaluating rats's model of lung cancer.
Keywords:Lung cancer  Wistar rats  Digital image
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