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An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes
Authors:Adam S. Dingens  Dana Arenz  Haidyn Weight  Julie Overbaugh  Jesse D. Bloom
Affiliation:1. Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA;2. Molecular & Cellular Biology PhD Program, University of Washington, Seattle, WA 98195, USA;3. Division of Human Biology and Epidemiology Program, Seattle, WA 98109, USA;4. Howard Hughes Medical Institute, Seattle, WA 98109, USA
Abstract:
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  • Keywords:deep mutational scanning  mutational antigenic profiling  BG505  antibody immunotherapy  virus evolution  immune escape
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