肝动脉超声监测肝硬化与肝功的相关性

目的探讨肝硬化肝动脉超声监测的临床意义及其与肝功的相关性。方法 130例肝硬化患者分成A、B两组,A组为乙肝病毒性肝硬化（80例）,B组为酒精性肝硬化（50例）,C组为正常对照（50例）,运用彩色多普勒技术分别监测两组患者肝动脉（HA）血流参数,包括肝动脉（HA）的内径（DHA）、收缩期峰值流速（PSVHA）、时间平均流速（TAMVHA）、阻力指数（RIHA）、搏动指数（PIHA）、血流量（QHA）,并与对照组比较。结果 A组较C组肝动脉PSVHA、QHA、RI、PI明显增加,与child分级呈正相关,B组较C组减少,与child分级呈负相关;A、B两组与C组间比较,差异有统计学意义（P〈0.05）。结论肝动脉血流动力学的特异性改变可作为判别不同病因所致肝硬化及其肝功损害程度最简单适用和相对稳定的评价指标,对肝硬化的预防和治疗具有重要意义。

Correlative study on the changes of hepatic artery hemodynamics by color Doppler ultrasonography in patients with cirrhosis

Objective To investigate the correlation between the changes of the hepatic artery hemodynamics and the Child Pugh grade in patients with cirrhosis by color Doppler.Methods 80 patients with chronic virus hepatitis（group A） and 50 patients with alcoholic cirrhosis（group B） underwent color Doppler ultrasonography of hepatic artery hemodynamics.At the same period,50 healthy people were considered as a control group.The hemodynamic parameters of hepatic artery were including DHA,PSVHA,TAMVHA,RIHA,PIHA and QHA.All the results in group A and group B were compared with control group.Results Comparing with control group,the PSVHA,QHA,RI and PI were significantly increased and were positive correlation with Child-Pugh grade in group A;the hemodynamic parameters above were significantly decreased and were negative correlation with Child-Pugh grade in group B.There was statistical significance of the hemodynamic parameters between the group A and group B（P 0.05）.Conclusion The specific changes of hepatic arterial flow can be considered as a criteria for the diagnosis of LC caused by different etiological factor,and it is important to the prevention and treatment of LC.