舌下微循环显微影像监测及其应用研究进展

微循环病变是导致组织低灌注的关键环节,对微循环进行监测在重症疾病中非常重要.舌体富含微血管,其中舌下微循环呈现网状结构,一定程度上反映活体组织微循环状态,是进行临床微循环监测和活体动物微循环检测的理想和重要部位.综述舌下微循环显微影像监测的设备、指标体系、应用情况.首先,综述监测设备,包括设备组成、探头采用的光学技术种...

Progress of Sublingual Microcirculation Microimage Monitoring and Application

Microcirculatory lesions are the key link leading to tissue hypoperfusion. Monitoring of microcirculatory lesions is very important in severe diseases. The tongue body is rich in microvessels,in which the sublingual microcirculation presents a reticular structure,reflecting the state of microcirculation in living tissue,and is an ideal and important site for clinical microcirculation monitoring and microcirculation detection in living animals. The equipment,index system,application,clinical significance and future prospect of sublingual microcirculation microimage monitoring were reviewed in this article. Firstly,we introduced the monitoring equipment,including the composition of the equipment,the types of optical technology adopted by the probe,the image processing algorithm adopted by the host,and the fixed form of the probe. Secondly,the index system of sublingual microcirculation microimage monitoring was summarized,including the perfusion quality index,vascular density index and perfusion heterogeneity index. Next,an example was given to illustrate the clinical and experimental applications,including the study on the relationship between diseases and microcirculation in clinical practice,the study on the relationship between drugs and microcirculation,and the study on the relationship between visceras’ microcirculation using sublingual microcirculation microimage monitoring technology. Finally,the significance of clinical diagnosis,treatment and research were discussed,and the technical improvement,development and application direction are prospected.