乙酰胆碱和幽门螺杆菌与慢性胃炎,消化性溃疡的关系

为探讨胆碱能神经功能和胃窦部幽门螺杆菌感染与慢性胃炎，消化性溃疡的关系，测定７６例慢性胃炎和消化性溃疡患者全血和肋液乙酰胆碱，并检测胃窦部幽门螺杆菌的感染指标，同时测定１８例健康对照全血Ａｃｈ。结果；Ａｃｈ与ＣＧ，Ｐｕ和对照组间，不同胃炎程度间，活动性与非活动性胃炎间以及Ｈｐ阳怀与阴性间均无显著性差异；

THE RELATIONSHIP OF ACETYLCHOLINE AND HELICOBACTER PYLORI WITH CHRONIC GASTRITIS AND PEPTIC ULCER

Whole blood and gastric juice acetylcholine (Ach) levels of 76 chronic gastritis (CG) and peptic ulcer (Pu) patients,and whole blood acetylcholine levels of 18 healthy controls were measured At the same time,helicobacter pylori (Hp) from the patients' gastric antrum were also examined The results showed that there were no significant differences in the Ach levels:among CG,Pu patients and the chontrols;in the different degrees of gastric inflammation;between active gastritis and non active gastritis patients;and between Hp positive and negative patients The Hp positive rate was higher in Pu patients than in CG patients,and higher in the active gastritis patieits than in the non active gastritis patients And such Hp positive rate increased along with the severity of the gastric inflammation.Pu healed and the gastric inflammation improved with the eradication of Hp The results suggest that Hp infection is one of the agents involved in the pathogenesis of CG and Pu,and that the disturbance of the colinergic nerve function may not be the main causal factor responsible for the pathogenesis of these two diseases