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| 不同表面处理的纯钛对血小板黏附特性的影响 | |
| 引用本文： | 张悦,夏海斌,王爱华,王贻宁,张婷.不同表面处理的纯钛对血小板黏附特性的影响[J].武汉大学学报(医学版),2007,28(4):507-510,F0003. |
| 作者姓名： | 张悦 夏海斌 王爱华 王贻宁 张婷 |
| 作者单位： | 1. 山西省红十字口腔医院,山西太原,030001 2. 武汉大学口腔医学院/口腔生物医学工程教育部重点实验室,湖北,武汉,430079 3. 华中科技大学材料学院,湖北,武汉,430074 |
| 摘 要： | 目的:观察钛-血小板相互作用时不同表面处理的纯钛对血小板黏附特性的影响。方法:将商业纯钛片制备成4种不同表面形貌的样本,即抛光表面、酸蚀表面、大颗粒喷砂加酸蚀表面、碱热处理表面,样本经扫描电镜观察及静态接触角分析后,在其表面滴加新鲜制备的富血小板血浆,30 min后进行扫描电镜观察。结果:大颗粒喷砂加酸蚀表面黏附的血小板最多,且形变明显;酸蚀表面血小板的黏附量也较多,但形变较少,以球形居多;抛光表面和碱热处理表面黏附的血小板很少,局部甚至缺无。结论:纯钛表面复杂的微形貌有利于血小板的黏附,钛表面的润湿性对血小板的黏附特性也有影响,亲水性表面不利于血小板的黏附。 |
| 关 键 词： | 纯钛 血小板黏附 表面微形貌 润湿性 |
| 文章编号： | 1671-8852（2007）04-0507-04 |
| 修稿时间： | 2007-03-22 |
Platelet Adhesion to Pure Titanium with Different Surface Treatment |
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| ZHANG Yue,XIA Haibin,WANG Aihua,WANG Yining,ZHANG Ting.Platelet Adhesion to Pure Titanium with Different Surface Treatment[J].Medical Journal of Wuhan University,2007,28(4):507-510,F0003. | |
| Authors: | ZHANG Yue XIA Haibin WANG Aihua WANG Yining ZHANG Ting |
| Institution: | 1School of Stomatology/Key Laboratory for Oral Biomedical Engineering of Ministry of Education, Wuhan University, Wuhan 430079, China; 2 College of Materials, Huazhong University of Science and Technology, Wuhan 430074 , China |
| Abstract: | Objective: To investigate the initial human platelet adhesion to pure titanium with different surface treatments.Methods: Pure titanium disks were prepared to form four kinds of surface as polished(Po),dual acid-etched(DAE),sandblasted and acid-etched(SLA),alkali-and heat-treated(AH).Platelet-rich plasma(PRP) were prepared and put into four kinds of surfaces of titanium disks.Then the samples were characterized by SEM after 30 minutes of incubation.Results: The amount of platelets on SLA and DAE were more than those on Po and AH.Platelets on SLA and DAE were widely distributed and aggregated.Platelets on SLA extended pseudopods clearly and linked with each other.Platelets on Po and AH were mainly round and distributed singly.Conclusion: Complex microtextures of titanium surface are favourable for the adherence of platelets.And the wettability has influence on platelets adhesion to titanium.Hydrophilic surfaces are against the adherence of platelets. |
| Keywords: | Pure Titanium Platelet Adhesiveness Surface Microtexture Wettability |
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