| 针刺对实验性大鼠胰岛素抵抗的逆转作用 |
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| 引用本文： | 易玮,许能贵,靳瑞.针刺对实验性大鼠胰岛素抵抗的逆转作用[J].广州中医药大学学报,2003,20(3):214-215. |
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| 作者姓名： | 易玮 许能贵 靳瑞 |
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| 作者单位： | 1. 广州中医药大学基础医学院,广州,510405
2. 广州中医药大学针灸推拿学院,广州,510405 |
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| 摘 要： | 目的]观察针刺对实验性胰岛素抵抗大鼠胰岛素抵抗的逆转作用。方法]将24只大鼠随机分成正常组、模型组和治疗组3组,每组8只。采用高糖饲料喂养方法复制胰岛素抵抗模型;观察针刺内关、足三里、三阴交以及肾俞等穴位对大鼠空腹血糖(FBG)、血浆胰岛素(PI)以及胰岛素敏感性指数(ISI)的影响。结果]模型组大鼠的FBG、PI均较正常组升高,而ISI则降低(均P<0.01);给予针刺治疗后,模型大鼠的FBG、PI均下降,而ISI则上升(与模型组比较,均P<0.01)。结论]针刺对胰岛素抵抗有一定的逆转作用。
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| 关 键 词： | 胰岛素抵抗 逆转作用 针灸疗法 动物模型 怍用机理 高脂血症 |
| 文章编号： | 1007-3213(2003)03-0213-02 |
| 修稿时间： | 2003年1月28日 |
Reversal Action of Acupuncture on Experimental Rats with Insulin Resistance |
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| YI Wei,XU Nenggui,JIN Rui.Reversal Action of Acupuncture on Experimental Rats with Insulin Resistance[J].Journal of Guangzhou University of Traditional Chinese Medicine,2003,20(3):214-215. |
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| Authors: | YI Wei XU Nenggui JIN Rui |
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| Abstract: | Objective] To observe the reversal action of acupuncture on experimental rats with insulin resistance. Methods] Twenty-four rats were randomized into normal group, control group and treatment group. Each group had 8 rats. Rat models with insulin resistance were induced by feeding of high-carbonhydrate forage. Fasting blood-glucose (FBG) and plasma insulin (PI) levels and insulin sensitivity index ( ISI) were examined after acupuncture of Neiguan ( PC6 ) , Zusanli ( ST36) , Sanyinjiao (SP6) and Shenshu (BL23). Results] FBG and PI levels were increased and ISI decreased in model group as compared with those in normal group ( P < 0.01). After acupuncture, FBG and PI levels were decreased and ISI increased in treatment group as compared with those in model group (P<0.01). Conclusion] Acupuncture exerts certain reversal actions on experimental rats with insulin resistance. |
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| Keywords: | INSULIN RESISTANCE /acup-mox therapy INSULIN/blood BLOOD GLUCOSE/analysis POINT PC6 (NEIGUAN) POINT ST36 (ZUSANLI) DISEASE MODELS ANIMAL |
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