| 埃索美拉唑与奥美拉唑治疗反流性食道炎的疗效观察 |
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| 引用本文： | 谭壮忱. 埃索美拉唑与奥美拉唑治疗反流性食道炎的疗效观察[J]. 中国医药导刊, 2008, 10(3): 416-417 |
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| 作者姓名： | 谭壮忱 |
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| 作者单位： | 内蒙古巴彦淖尔市医院消化内科,巴彦淖尔,015000 |
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| 摘 要： | 目的:探讨埃索美拉唑与奥美拉唑治疗反流性食道炎的疗效。方法:共选反流性食道炎患者24例,12例给予埃索美拉唑20mg,每日2次,12例给予奥美拉唑20mg,每日2次,疗程4周。治疗期间禁用其他抑酸类及胃黏膜保护药,但可同用胃动力药。治疗前后分别记录患者症状积分改变及24小时食管pH<4的总时问百分比为总体参数来进行评判。结果:两种药物治疗后症状:埃索美拉唑为(0.7±0.5),奥美拉唑为(15.2±4.8),埃索美拉唑症状完全缓解率达97%。pH值<4的总时间百分比比较:治疗后奥美拉唑为(9.3%±7.4%),埃索美拉唑为(0.98%±0.87%),病理性酸反流恢复正常达100%,两种药物治疗后差异有显著性变化。结论:埃索美拉唑与奥美拉唑治疗反流性食道炎均有效,但埃索美拉唑疗效更好。
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| 关 键 词： | 埃索美拉唑 奥美拉唑 反流性食道炎 症状 埃索美拉唑 奥美拉唑 药物治疗 反流性食道炎 疗效观察 Esomeprazole Esophagitis 显著性变化 差异 常达 恢复 酸反流 病理性 比较 完全缓解率 结果 总体参数 百分比 时间 食管 |
Curative Survey of Flowing-Back Esophagitis between Esomeprazole and Omepraxole |
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| Tan Zhuang-chen. Curative Survey of Flowing-Back Esophagitis between Esomeprazole and Omepraxole[J]. Chinese Journal of Medicinal Guide, 2008, 10(3): 416-417 |
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| Authors: | Tan Zhuang-chen |
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| Affiliation: | Tan Zhuang-chen (Digestive Department of Bayannao'er City Hospital in Inner Mongolia,Bayannao'er 015000,China) |
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| Abstract: | Objective:Inquire into the curative effect of flowing-back esophagitis between esomeprazole and omeprazole.Meth- ods:We chose 24 patients with flowing-back esophagitis and let 12 of them take esomeprazole twice a day and the other 12 have ome- prazole twice a day for 4 weeks.During this curative time we forbade the patients having anti-acid and protecting gastric membrane drugs,but they could use the medicine that promoted gastric peristalsis.We recorded the patients' cumulative scoring of symptoms change b... |
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| Keywords: | Esomeprazole Omeprazole Flowing-back esophagitis Symptoms |
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