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西洋参茎叶皂甙对某些免疫功能影响的实验研究
引用本文:吕忠智,王德凯,刘禹,谷春莉,杜霞. 西洋参茎叶皂甙对某些免疫功能影响的实验研究[J]. 牡丹江医学院学报, 1993, 0(1)
作者姓名:吕忠智  王德凯  刘禹  谷春莉  杜霞
作者单位:白求恩医科大学(吕忠智),白求恩医大基础医学师资班(王德凯,刘禹),牡市先锋医院(谷春莉),牡市先锋医院(杜霞)
摘    要:作者从西洋参茎叶中提得总皂甙(panaxquinquefolium sapoin)简称PQS,观察了PQS对免疫功能的影响。结果PQS体内给药8天后100mg/kg组T、B淋巴细胞转化率显著高于对照组(P<0.05);可促进conA诱导IL—2产生(P<0.05);脾脏T细胞百分率及B细胞的抗体产生水平均显著高于对照组(P<0.01),说明在100mg/kg剂量下,机体的T、B淋巴细胞功能都有明显的增强作用。

关 键 词:西洋参  总皂甙  T、B淋巴细胞

Influence of PQS on immune functions in mice
Lu Zhong-zhi,et al Dept.of Pharmacology,Bethune Medical University. Influence of PQS on immune functions in mice[J]. Journal of Mudanjiang Medical College, 1993, 0(1)
Authors:Lu Zhong-zhi  et al Dept.of Pharmacology  Bethune Medical University
Abstract:The influence of PQS (panaxquinquefolium saponin extracted from pana-quilon) on immune functions was observed in mice. The result showed that on the 8 th day of taking PQS the group given PQS at a dose of 100mg/kg had significantly higher T and B lymphocyte transformation rate (P<0.05), higher percentage of spleen's T cell (P<0.01) and higher level of antibody producedby B cell (P<0.01) respectively than control group did and PQS significantly promoted ConA to induce IL-2 (P<0.05).It is indicated that PQS at a dose of 100mg/kg may improve the functions of T and B cells.
Keywords:PQS (panax quinquefolium saponin)  T and B cells
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