| 急性桐油中毒大鼠实验模型的建立及其形态学改变 |
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| 引用本文： | 王洪超.急性桐油中毒大鼠实验模型的建立及其形态学改变[J].首都医学院学报,1998,19(1):5-8. |
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| 作者姓名： | 王洪超 |
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| 作者单位： | 首都医科大学病理解剖学教研室，西城区德外医院内科 |
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| 摘 要： | 模拟人类桐油中毒的方式，以不同剂量桐油灌喂大鼠，制作大鼠急性桐油中毒的模型。发现：不同剂量的桐油可引起不同程度的肺脏、肝脏、肾脏和心脏的损伤。而且，各脏器的损伤程度随着灌喂剂量的增加而增加。结果提示急性桐油中毒可以导致全身多个器官的损伤。
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| 关 键 词： | 桐油中毒 实验模型 形态变化 |
| 收稿时间： | 1997-09-29 |
Morphologic Changes of Rat Model of Moentjang Tina |
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| Wang Hongchao,Chen Ruifen,Song Aili,Liu Guozhen,Han Zhengzheng,Yao Yaling.Morphologic Changes of Rat Model of Moentjang Tina[J].Journal of Capital University of Medical Sciences,1998,19(1):5-8. |
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| Authors: | Wang Hongchao Chen Ruifen Song Aili Liu Guozhen Han Zhengzheng Yao Yaling |
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| Institution: | 1. Department of Pathology, Capital University of Medical Sciences;2. Department of Internal Medicine, Dewai Hospital Xicheng District |
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| Abstract: | Rat model of Moentjang tina was produced by imitating Moentjang tina of human beings with different dose of Tung oil(Aleuriter fordii), which had made 55 people poisoned. The result showed that different pathological changes, such as interstitial edema of lung, hydropic degeneration of proximal tubule, fatty degeneration of hepatocyte and loose cytoplasm of myocardium, happened in groups of different dose of Tung oil, and that the severity of injury paralleled somewhat to the amount of oil used. The experiment indicates that Tung oil can cause comprehensive injuries of different organs. |
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| Keywords: | Moentjang tina rat model morphologic changes |
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