| 银杏叶聚戊烯醇抗癌作用的初步研究 |
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| 引用本文： | 高凌,亢寿海,张琴芬,张能芳,钱新华,徐荣华.银杏叶聚戊烯醇抗癌作用的初步研究[J].药学与临床研究,2003,11(1):1-3. |
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| 作者姓名： | 高凌 亢寿海 张琴芬 张能芳 钱新华 徐荣华 |
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| 作者单位： | 江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所 |
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| 基金项目： | 江苏省科技厅社会发展项目资助 (BS2001065) |
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| 摘 要： | 目的:研究银杏叶(Folium Ginkgo)提取物—聚戊烯醇(Polyprenols GP-1)的抗肿瘤作用。方法:采用动物抗移植性肿瘤实验方法。结果:10.0mg/kg的聚戊烯醇对移植性肝癌Heps和肉瘤S180的实验抑制率分别为49.13%和46.53%,40.0mg/kg的聚戊烯醇对艾氏癌EC抑制率为49.65%(P<0.01)。银杏叶聚戊烯醇对艾氏腹水癌EAC小鼠无明显延长寿命作用。结论:银杏叶聚戊烯醇有良好的抗肿瘤作用,应进行深入研究。
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| 关 键 词： | 聚戊烯醇 抗肿瘤 Heps S180 EAC |
| 收稿时间： | 2002/6/5 0:00:00 |
A Preliminary Study of Antitumor Effects of Polyprenols Extracted from Folium Gingko |
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| Gao Ling,Kang Shouhai,Zhang Qinfen,Zhang Nengfang,Qian Xinhua and Xu Ronghua.A Preliminary Study of Antitumor Effects of Polyprenols Extracted from Folium Gingko[J].Pharmacertical and Clinical Research,2003,11(1):1-3. |
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| Authors: | Gao Ling Kang Shouhai Zhang Qinfen Zhang Nengfang Qian Xinhua and Xu Ronghua |
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| Abstract: | Objective:to study the effects of Polyprenols (GP-1),an extract of Folium Gingko, on tumor .Methods:Using grafting tumor models in mice to detect the inhibitory rates. Results:The inhibitory rates were 49.13% and 46.53% on Heps and S180 respectively when GP-1 was given orally at the dose of 10.0mg/kg;And the inhibitory rate was 49.65% on EAC at the dose of 40.0mg/kg,but GP-1 had no effect of prolonging lifespan. Conclusion:GP-1 had significant antitumour effects,it''s worthy to do some additional research. |
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| Keywords: | Polyprenols Antitumour HEPS S180 EAC |
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