Adenosarcoma of the uterus following tamoxifen treatment for breast cancer |
| |
| Authors: | Mourits,Hollema,Willemse,de Vries,Aalders,& van der Zee |
| |
| Affiliation: | Department of Gynecology, University Hospital, Groningen, the Netherlands; Pathology, University Hospital, Groningen, the Netherlands; Medical Oncology, University Hospital, Groningen, the Netherlands |
| |
| Abstract: | Mourits MJE, Hollema H, Willemse PHB, De Vries EGE, Aalders JG, Van der Zee AGJ. Adenosarcoma of the uterus following tamoxifen treatment for breast cancer. Int J Gynecol Cancer 1998; 8 : 168–171.
A 71-year-old patient developed an uterine adenosarcoma two months after two years of tamoxifen adjuvant treatment for early breast cancer. After curettage for postmenopausal bleeding, the patient underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. Histologic examination revealed an adenosarcoma of the uterus without myometrial invasion or lymphatic spread. After four years of follow-up, there was no evidence of recurrent disease. The possible association between tamoxifen treatment and uterine sarcoma is discussed. |
| |
| Keywords: | tamoxifen uterine adenosarcoma |
|
|
