马齿苋胶囊加中药灌肠治疗溃疡性结肠炎临床疗效分析

目的观察马齿苋胶囊加中药结肠炎灌肠液对溃疡性结肠炎(UC)的疗效及不良反应。方法69例UC病人,随机分为治疗组35例,给予口服马齿苋胶囊,同时给予结肠炎灌肠液200 mL灌肠,每日1次;对照组34例给予口服柳氮磺胺吡啶片。比较两组在临床症状、肠镜下、组织学方面的变化。结果两组在临床症状、肠镜下表现、组织学进步方面(总有效率分别为91.42%和76.47%,85.71%和61.76%,77.14%和61.76%),差异具有显著性意义(P<0.01)。结论马齿苋胶囊配合结肠炎灌肠液治疗UC疗效满意,不良反应小。

Clinical Efficacy Analysis of Purslane Capsules Combining TCM Enema in the Treatment of Ulcerative Colitis

Objective To observe the efficacy and adverse reactions of purslane capsules combining TCM enema in the treatment of ulcerative colitis(UC).Methods 69 cases of UC patients were randomly divided into two groups: 35 cases in the theropeutic group were given purslane capsules for oral usage,and were given colitis enema at the same time,1 time a day;34 cases in the control group were given salazosulfapyridine tablets.The changes of clinical synptoms,expressions under enteroscope and histology of the two groups were compared.Results The clinical synptoms,expressions under enteroscope and histological improvement of the two groups were different(the total effective rates were 91.42 % and76.4 %,85.71 % and 61.76 %,77.14 % and 61.76 %),and the difference was significant(P<0.01).Conclusion Purslane capsules combining colitis enema has a favorate effect for the treatment of UC,and has few adverse reactions.