金银花中黄酮类化合物的研究进展

对近5年来金银花中黄酮类化合物的化学成分、提取分离、含量测定、药理作用等方面进行总结,为进一步开发利用金银花黄酮类化合物提供依据。金银花黄酮类化合物的提取方法较为成熟包含乙醇回流、水、超声辅助、超高压、超临界流体提取法,但分离纯化方法相对较少仅有大孔树脂柱及聚酰胺柱色谱法;其含量测定主要采用紫外分光光度法,次之为HPLC及荧光光度法;金银花黄酮类化合物具有抗氧化及抗自由基、抗菌抗病毒、保肝作用,其保护心血管、消化系统、抗炎及抗免疫、抗肿瘤、镇痛等作用仍需广大医药工作者进一步深入研究。

Research Progress of Flavonoids on Lonicerae japonicae Flos in Last Five Years

This study aims to summarize the research advances on composition, extraction, detection, physiological activity and provides scientific foundation for the development and utilization of flavonoids from L.japonicae Flos in last five years.The methods of flavonoids extraction from L. japonicae Flos are more mature than separation and purification which are relatively less. Its main content determination is by ultraviolet spectrophotometry,and HPLC is second. The physiological activity of antioxidant,antibacterial and liver protective effect have been reported,so more researches need medical workers to be done is to explain its protect cardiovascular,digestive system,anti-inflammatory and anti-immune,antitumor and analgesic effects.