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高同型半胱氨酸与冠心病的相关性分析
引用本文:陆兆华,卢谦,许北柱,莫春妍,杨宗旺.高同型半胱氨酸与冠心病的相关性分析[J].牡丹江医学院学报,2013(4):24-26.
作者姓名:陆兆华  卢谦  许北柱  莫春妍  杨宗旺
作者单位:梧州市人民医院心内科,广西梧州543000
摘    要:目的:探讨高同型半胱氨酸(Hcy)与冠心病的相关性。方法:选择我院确诊的100例冠心病患者作为观察组,另外随机选择100例体检健康者作为对照组,应用循环酶法检测两组血清Hcy水平,对比分析其差异。结果:观察组血清Hcy值(23.66±10.48)umol/L高于对照组(8.47±3.45)umol/L,且观察组高同型半胱氨酸血症的发生率明显大于对照组,差异有统计学意义,P<0.05。结论:高同型半胱氨酸和冠心病的发病率以及严重程度密切相关,可以作为临床诊断中的独立危险因素。

关 键 词:冠心病  同型半胱氨酸  高同型半胱氨酸血症

ANALYSIS OF THE CORRELATION BETWEEN HOMOCYSTEINE AND CORONARY HEART DISEASE
Institution:Lu Zhao Hua et al (Department of Cardiology, the People Hospital in Wuzhou City in Guangxi Zhuang Autonomous Region, Wuzhou 543000, China)
Abstract:Objective:To investigate the correlation between homocysteine and coronary heart disease. Methods :100 patients with coronary heart disease diagnosed in our hospital as the observation group , another randomly selected 100 cases of healthy subjects as the control group, by cyclic enzymatic detection in serum Hcy levels, comparative analysis of the differences. Resalts:The serum Hcy values ( 23.66 ~ 10.48 ) umol / L higher than those in the control group ( 8.47 ~ 3.45 ) umol / L, and the incidence of hyperho- mocysteinemia in the observation group was significantly greater than that of the control group, the difference was statistically signifi- cant, P 〈 0.05 . Conclusion: High homocysteine and coronary heart disease incidence and severity are closely related and can be used as an independent risk factor in the clinical diagnosis.
Keywords:coronary heart disease  homocysteine  high hyperhomocysteinemia
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