高同型半胱氨酸与冠心病的相关性分析 |
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引用本文: | 陆兆华,卢谦,许北柱,莫春妍,杨宗旺.高同型半胱氨酸与冠心病的相关性分析[J].牡丹江医学院学报,2013(4):24-26. |
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作者姓名: | 陆兆华 卢谦 许北柱 莫春妍 杨宗旺 |
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作者单位: | 梧州市人民医院心内科,广西梧州543000 |
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摘 要: | 目的:探讨高同型半胱氨酸(Hcy)与冠心病的相关性。方法:选择我院确诊的100例冠心病患者作为观察组,另外随机选择100例体检健康者作为对照组,应用循环酶法检测两组血清Hcy水平,对比分析其差异。结果:观察组血清Hcy值(23.66±10.48)umol/L高于对照组(8.47±3.45)umol/L,且观察组高同型半胱氨酸血症的发生率明显大于对照组,差异有统计学意义,P<0.05。结论:高同型半胱氨酸和冠心病的发病率以及严重程度密切相关,可以作为临床诊断中的独立危险因素。
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关 键 词: | 冠心病 同型半胱氨酸 高同型半胱氨酸血症 |
ANALYSIS OF THE CORRELATION BETWEEN HOMOCYSTEINE AND CORONARY HEART DISEASE |
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Institution: | Lu Zhao Hua et al (Department of Cardiology, the People Hospital in Wuzhou City in Guangxi Zhuang Autonomous Region, Wuzhou 543000, China) |
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Abstract: | Objective:To investigate the correlation between homocysteine and coronary heart disease. Methods :100 patients with coronary heart disease diagnosed in our hospital as the observation group , another randomly selected 100 cases of healthy subjects as the control group, by cyclic enzymatic detection in serum Hcy levels, comparative analysis of the differences. Resalts:The serum Hcy values ( 23.66 ~ 10.48 ) umol / L higher than those in the control group ( 8.47 ~ 3.45 ) umol / L, and the incidence of hyperho- mocysteinemia in the observation group was significantly greater than that of the control group, the difference was statistically signifi- cant, P 〈 0.05 . Conclusion: High homocysteine and coronary heart disease incidence and severity are closely related and can be used as an independent risk factor in the clinical diagnosis. |
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Keywords: | coronary heart disease homocysteine high hyperhomocysteinemia |
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