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| 重组人生长激素在成人生长激素缺乏症的应用 | |
| 引用本文： | 李丙蓉,郑宏庭,杨泉.重组人生长激素在成人生长激素缺乏症的应用[J].心血管病学进展,2010,31(3):479-482. |
| 作者姓名： | 李丙蓉 郑宏庭 杨泉 |
| 作者单位： | 1. 四川省第四人民医院内分泌科,四川,成都,610016 2. 第三军医大学附属新桥医院内分泌科,重庆,400037 3. 四川省第四人民医院心血管内科,四川,成都,610016 |
| 摘 要： | 近20年来,重组生长激素已可以无限量的制备。近年来的研究已阐明成人生长激素缺乏的影响及生长激素替代治疗的益处。成人生长激素缺乏症对人影响最大的是生活质量、骨骼健康及包括血清脂质谱、身体构成变化的心血管危险因子的改变,而这也正是生长激素替代治疗获益最显著之处。大量的证据显示了重组人生长激素治疗的疗效,尤其在改善骨代谢和改善心血管危险因素等多方面发挥作用,并且是安全的。 |
| 关 键 词： | 成人生长激素缺乏症 人生长激素替代疗法 |
Application of Recombinant Human Growth Hormone in Adults with Growth Hormone Deficiency |
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| LI Bing-rong,ZHENG Hong-ting,YANG Quan.Application of Recombinant Human Growth Hormone in Adults with Growth Hormone Deficiency[J].Advances in Cardiovascular Diseases,2010,31(3):479-482. | |
| Authors: | LI Bing-rong ZHENG Hong-ting YANG Quan |
| Institution: | LI Bing-rong,ZHENG Hong-ting,YANG Quan,LI Xiu-jun(1.Department of Endocrinology,The Fourth People＇s Hospital of Sichuan Province,Chengdu 610016,China;2.Department of Endocrinology,Xinqiao Hospital Affiliated to The Third Military Medical University,Chongqing 400037,China;3.Department of Cardiology,The Fourth People＇s Hospital of Sichuan Province,Chengdu 610016,China;4.Department of Endocrinology,West China Hospital of Sichuan University,Chengdu 610041,China) |
| Abstract: | Limitless supplies of recombinant human growth hormone（HGH） have been available for the last 20 years.During this period,studies have characterized the effects of HGH deficiency in adults and the benefits of HGH replacement therapy.The areas of greatest impairment and benefit are： quality of life,skeletal health,and cardiovascular risk factors.By optimizing HGH replacement therapy at various stages of adult life,it is hoped that it will prevent the development of osteoporosis and reduce the mortality and morbidity associated with hypopituitarism.The benefits of HGH treatment have been shown to be sustained over several years,and the long-term surveillance of patients continues. |
| Keywords: | adult-onset growth hormone deficiency human growth hormone replacement therapy |
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