兔P_(3a)波的立体分布研究

目的探讨P300亚成份P3a波的神经起源。方法兔头颅表面选取多个有代表性的点为探测点，所有记录点均在大脑半球两侧对称部位不同深度先后测试ERPs，并观察Pu波的空间分布特点，推测出P3a 波的可能起源部位。结果头颅各记录点不同深度的P3a波潜伏期无显著性差异(P >0.05)。acg5点的颅骨下P3a波极性翻转率最高(P< 0.05),且acg5及毗邻点acg4未翻转的P3a波都具有电位梯度(7mm处波幅最大)，在其附近的F3(F4)、acg3及acg7等点颅骨P3a波有中等度的电位梯度，而其它点颅内P3a波的电位梯度变化相对较小或无规律。结论兔acg5与acg4两点颅骨下6～7mm附近区域(Brodmann25、32区)可能是兔P3a波的起源。

Study on space distribution of rabbit P3a potential

Objective To investigate possible nerological origination of rabbit P3a potential. Method we simultaneously recorded the ERPs at dura and various depths beneath the skull in a point of rabbit skull, similarly did some in different points of rabbit skull. Result In the Brodmann 25 and 32 areas(AcgI), the polarity of P3a to those at dura was markedly reverse and the reverse rate of P3a(81.3%) was significantly higher than other locations, the P3a without polarity reversal showed steep voltage gradient. There was an increasing trend of the P3a reversal and moderate voltage gradient nearby the AcgI, but not other regions. Conclusion Rabbit P3a potential possibly originate from the AcgI acea.