灵芝对小鼠学习记忆和单胺类神经递质的影响

目的：观察灵芝对小鼠智力的影响。方法：灵芝水煎剂以每100g体重1ml（低剂量组为5g/kg，高剂量组为10g/kg）连续灌胃2周，测定学习记忆和单胺类神经递质。结果：与对照组相比，灵芝能显著提高小鼠大脑5－羟色胺和多巴胺的含量（P＜0.05），明显增强小鼠的学习能力（P＜0.01），对小鼠的自发活动具有一定的抑制作用。结论：灵芝具有明显抗衰益智的作用。

Effects of Ganoderma lucidum on Learning Memory and Monoamine Neurotransmitter''''s Content in Mice

Objective:The effect of Ganoderma lucidum on wit in mice was observed. Methods:The ability of learning and memory and the content of monoamine neurotransmitters were measured after the mice were kept on giving the water extract of Ganoderma lucidum ig.5 g/kg body weight in low dose group and ig. 10g/kg in high dose group for two weeks. Results: Ganoderma lucidum caused significant increase in the ability of learning and memory, and in 5 hydroxytryptamine and dopamine level of cerebrum in mice. It also caused decrease in spontanous aciton in mice. Conclusion: Ganoderma lucidum had the effects on delaying senecence and profiting wit.