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Synthesis and antifungal activity of (+/-)-1-(5-aryl-3-pyridin-2-yl-4,5-dihydro-pyrazol-1-yl)-2-imidazol-1-yl-ethanone derivatives |
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| Authors: | Mamolo Maria Grazia Zampieri Daniele Falagiani Valeria Vio Luciano Banfi Elena |
| Institution: | Dipartimento di Scienze Farmaceutiche, Università di Trieste, Piazzale Europa 1, I-34127, Trieste, Italy. mamolo@univ.trieste.it |
| Abstract: | (+/-)-1-(5-Aryl-3-pyridin-2-yl-4,5-dihydro-pyrazol-1-yl)-2-imidazol-1-yl-ethanone derivatives were synthesized and tested for their in vitro antifungal activity. The compounds showed a moderate activity against strains of Candida parapsilosis, Candida pseudotropicalis and Candida glabrata. |
| Keywords: | (±)-1-(5-Aryl-3-pyridin-2-yl-4 5-dihydro-pyrazol-1-yl)-2-imidazol-1-yl-ethanone derivatives Antifungal activity Candida spp |
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