鞍区肿瘤的脑电图特征(附224例分析)

目的：探索鞍区肿瘤的脑电图（EEG）特征。方法：224例经手术和(或)病理、CT、MRI证实的鞍区肿瘤分成3组：（1）垂体腺瘤组153例；（2）颅咽管瘤组46例；（3）鞍区其他肿瘤组25例。所有患者均按常规方法在手术前2-30 d内记录EEG。结果：过半数的患者（57．6％）呈现正常或轻度异常EEG，其余患者（42．4％）表现EEG异常,其中弥漫性异常29．0％，阵发性异常8．5％，局灶性异常4．9％。此外,有24例（10．7％）出现间歇性节律性δ活动（IRDA）,77例（34．4％）有生理波抑制现象。IRDA及生理波抑制在颅咽管瘤组中的出现率明显高于其他两组。直径＞20 mm的鞍区肿瘤EEG异常率高。结论：鞍区肿瘤的EEG以无特征性改变占主导地位，其EEG异常的主要表现形式是弥漫性及阵发性异常，少有局灶性异常出现。肿瘤体积与异常程度呈正相关。EEG对鞍区肿瘤的定性诊断有一定帮助。

The EEG of sella turcica region tumor: an analysis of 224 cases

Objective: To investigate the characteristics of the electron encephalogram (EEG) of the sella turcica region tumor (STRT). Methods: Two hundred and 24 patients with STRT, confirmed by surgery, pathology, CT or MRI, were divided into 3 groups: (1) Pituitary adenoma (153 cases). (2) Craniopharyngioma(46 cases). (3) Other tumors in sella turcica region (25 cases). EEG were recorded with conventional method 2-30 days before operation. Results: Over half of the patients (56.7%) had normal or mild abormal EEGs. The rest of the patients had diffuse abnormal EEGs (29.0%), paroxysmal abnormal EEGs (8.5%) or local abnormal EEGs(4.9%). 24 cases displayed intermittent rhythmic delta activities (IRDA, 10.7%). Seventy-seven cases showed an inhibition of physiological waves. IRDA and inhibition of physiological waves frequently appeared in the EEGs of the craniopharyngioma group. The rate of the abnormality of EEG in the patients with large tumor (D>2 cm) was higher than that of the patients with small tumor (D<2 cm). Conclusion: Non -specific changes in EEG are the predominant manifestations in STRT. The main characteristics of the abnormal EEGs in STRT are diffuse or paroxysmal abnormality. Only a few cases have local abnormal EEGs. The extent of abnormality in EEGs correlates to the size of tumor. EEG is helpful in qualitative diagnosis of STRT