合并HIV感染的梅毒特点

梅毒可以促进HIV的传播,由于机体免疫系统的抑制,从而导致合并HIV感染的梅毒患者和未合并HIV感染的梅毒患者的疾病过程不同.合并HIV感染的梅毒患者可有一些不典型和较严重的临床表现,病程进展加速,梅毒血清反应假阴性和经充分治疗后血清复发率及常规苄星青霉素治疗失败率均较非合并HIV感染的梅毒增高.合并HIV感染的梅毒患者累及心血管的时间缩短,神经梅毒的发生率也有一定程度的增高.

Syphilis in HIV-infected patients

Syphilis may facilitate the acquisition and transmission of human immunodefieieney virus (HIV).As a result of immune system suppression.the coupe of syphilis in HIV-infected patients difiers from that in non-HIV-infected patients.Syphilis in HIV-infected patients may be associated with some atypical and severe clinical manifestations,a rapid progression and an increase in false-negative rate for syphilis serum reaction,incidence of neurosyphilis,serum recurrence and in treatment failure with benzathine penicillin.Besides,the progression to cardiovascular syphilis may be accelerated in HIV-infected syphilic patients.