| EMIA—ALK与非小细胞肺癌相关研究进展 |
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| 引用本文： | 王梦,杨继元. EMIA—ALK与非小细胞肺癌相关研究进展[J]. 国外医学(肿瘤学分册), 2012, 0(11): 848-850 |
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| 作者姓名： | 王梦 杨继元 |
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| 作者单位： | 长江大学附属第一医院肿瘤科,荆州434100 |
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| 摘 要： | EMIA—ALK是新近发现的主要表达于非小细胞肺腺癌中的融合基因，多出现在年轻的轻度吸烟或非吸烟患者中，ALK抑制剂crizotinib治疗EMIA—ALK阳性非小细胞肺癌有很高的应答率，其出现进一步完善了非小细胞肺癌的个体化治疗。
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| 关 键 词： | 癌 非小细胞肺 肺肿瘤 肿瘤标记 |
EMIA-ALK fusion gene in non-small cell lung cancer |
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| WANG Meng,YANG Ji-yuan. EMIA-ALK fusion gene in non-small cell lung cancer[J]. Foreign Medical Sciences (Cancer Section), 2012, 0(11): 848-850 |
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| Authors: | WANG Meng YANG Ji-yuan |
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| Affiliation: | . Department of Medical Oncology, the First Affiliated Hospital, Yangtze University, Jingzhou 434100, China |
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| Abstract: | EMIA-ALK fusion oncogene represents a new molecular target which appears mainly in lung adenoearcinoma. EMIA-ALK is detected more frequently in young non-small-cell lung cancer patients who never or light smoke. ALK inhibitors（crizotinib） for the treatment of the EMIA-ALK-positive non-small cell lung cancer has a high response rate. This finding can improve the individual treatment of non-small cell lung cancer. |
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| Keywords: | Carcinoma, non-small-cell Lung neoplasms Tumor markers |
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