丙型病毒性肝炎的研究进展

丙型病毒性肝炎由丙型肝炎病毒（HCV）感染所致.HCV感染呈全球分布,我国是高流行地区,由于HCV基因的高变性,容易逃避机体免疫系统的清除.HCV感染免疫系统细胞,造成机体对HCV感染的免疫应答异常,并引起组织的损伤,导致肝细胞的慢性持续性感染,并可进一步发展成肝硬化,甚至肝细胞肝癌.HCV主要经血液传播,包括输血与血制品传播、静脉吸毒、针刺、医源性传播、性接触和母婴垂直传播等.

Development of Study on Hepatitis C

The hepatitis C is commonly caused by the HCV which is widespead distributed in the world. Our country is a high popular area the HCV gene has high variability and easy escape the clearance from body immune system. The HCV infects immune celld and causes the abnormal immune response and tissue damage. All these could cause chronic and persistent infection of hepatic cell and in next step that might induce cirrhosis and even carcinoma. The Key HCV dissemination is via blood route which include blood transtasfusion houup, sex behavior and mother- child, etc.