封闭式负压引流联合超声清创术治疗 糖尿病足溃疡的疗效

目的 观察封闭式负压引流（VSD）联合超声清创术（UDM）在糖尿病足（DF）溃疡创面愈合中 的应用。方法 选取DF 溃疡患者153 例，按入院先后顺序随机分为VSD 联合UDM（VSD+UDM）组77 例和 VSD 组76 例。比较两组入院第7 天时的细菌清除率、创面面积、创面缩小面积、创面缩小率，以及出院时创 面愈合时间、住院时间、换药次数、住院费用和治疗前后经皮氧分压。结果 入院第7 天，两组比较，VSD+ UDM 组细菌清除率、创面缩小面积及创面缩小率均高于VSD 组，创面面积低于VSD 组，差异有统计学意义 （P <0.05）。VSD+UDM 组创面愈合时间、换药次数及住院费用均低于VSD 组，差异有统计学意义（P <0.05）。 两组经皮氧分压比较，治疗前差异无统计学意义（P >0.05），治疗后VSD+UDM 组较VSD 组增高，差异有统 计学意义（P <0.05）。结论 VSD 联合UDM 治疗DF 溃疡可促进创面愈合，缩短创面愈合时间和住院时间， 治疗效果较传统换药联合VSD 更显著。

Effect of ultrasonic debridement machine combined with vacuum sealing drainage in diabetic foot ulcer healing

Objective To observe the effect of ultrasonic debridement machine (UDM) combined with vacuum sealing drainage (VSD) in diabetic foot (DF) ulcer healing. Methods A total of 153 cases with DF ulcer were divided into VSD+UDM group (n = 77) and VSD group (n = 76) according to the order of admission. The bacterial clearance rate, wound surface, wound surface reduction, wound surface reduction rate and other related index were compared. Results The bacterial clearance rate, wound surface reduction and wound surface reduction rate were higher, while wound surface was lower in VSD+UDM group than in VSD group (P < 0.05 or P < 0.01). The surface healing time, dressing times and hospital stays were lower in VSD+UDM group than in VSD group (P < 0.05 or P < 0.01). There was no statistical significance on transcutaneous oxygen pressure before treatment, and compared with VSD group, the transcutaneous oxygen pressure was reduced after treatment. Conclusion UDM combined with VSD in DF ulcer healing can promote wound healing, reduce the healing time, hospital stays and hospitalization costs. The treatment effectiveness of UDM+VSD is more prominent than traditional treatment combined with VSD.