| 变应性鼻炎的发病机制与精准治疗 |
| |
| 引用本文： | 顾瑜蓉,李华斌. 变应性鼻炎的发病机制与精准治疗[J]. 中国耳鼻咽喉颅底外科杂志, 2019, 25(6): 578-584 |
| |
| 作者姓名： | 顾瑜蓉 李华斌 |
| |
| 作者单位： | 复旦大学附属眼耳鼻喉科医院 耳鼻咽喉科,上海200031 |
| |
| 基金项目： | 国家自然科学基金杰出青年基金（81725004）。 |
| |
| 摘 要： | 目的变应性鼻炎临床上以鼻痒、喷嚏和流涕为典型特征，是一种变应原特异性IgE介导的鼻黏膜慢性炎症，目前治疗包括变应原回避、药物治疗、免疫治疗和手术治疗。基于不同免疫表型的精准治疗代表了变应性鼻炎治疗的未来方向。
|
| 关 键 词： | 变应性鼻炎|治疗| 发病机制 |
Allergic rhinitis: pathogenesis and precision medicine |
| |
| GU Yu-rong,LI Hua-bin. Allergic rhinitis: pathogenesis and precision medicine[J]. Chinese Journal of Otorhinolaryngology-skull Base Surgery, 2019, 25(6): 578-584 |
| |
| Authors: | GU Yu-rong LI Hua-bin |
| |
| Affiliation: | Department of Otorhinolaryngology, Affiliated Ophthalmology and Otolaryngology Hospital of Fudan University, Shanghai 200031, China |
| |
| Abstract: | Abstract:ObjectiveAllergic rhinitis, a chronic inflammatory cascade in nasal mucosa mediated by allergen specific IgE, is clinically characterized by pruritus, sneezing and rhinorrhoea. Current therapeutic strategy includes allergen avoidance, pharmacotherapy, immunotherapy and surgery. Precision medicine, based on immunological phenotypes, indicates the future therapeutic direction for the treatment of allergic rhinitis. |
| |
| Keywords: | Allergic rhinitis|Treatment|Pathogenesis |
|
| 点击此处可从《中国耳鼻咽喉颅底外科杂志》浏览原始摘要信息 |
|
点击此处可从《中国耳鼻咽喉颅底外科杂志》下载全文 |
