不同Child分级肝硬化患者应用二维斑点追踪技术测量左心室功能指标差异分析

【】目的：应用二维斑点追踪技术分析肝硬化患者左心室功能的指标差异。方法：随机抽取我院68例肝硬化患者,并按Child分级分为A、B、C级三组,和28例正常人做为对照组。利用二维斑点追踪技术对所有试验者进行现场操作,并获取Child A、B、C级三组肝硬化实验组和对照组的左心室16节段横纵及立体方向的最高收缩期数值,从而分析不同Child分级肝硬化患者的心室功能指标差异。结果：三组肝硬化患者的收缩压、舒张压及脉压差都低于对照组,但心率高于对照组,差异具有统计学意义(P<0.05)；除左心室侧壁心尖节段的最高收缩期数值无统计学意义外,Child A、B、C级三组肝硬化实验组左心室其他各节段的横纵及立体方向的最高收缩期数值都低于对照组,差异有统计学意义(P<0.05)；Child A、B、C级三组肝硬化实验组左心室心尖段、中间段及基底段的最高收缩期数值两两互相比较,Child C级组最低,Child A级最高,差异有统计学意义(P<0.05)。结论：肝硬化患者有左心室部分节段收缩力下降的并发症,且随着Child级数越高(C级>B级>A级)左心室越多节段会发生收缩力下降的现象,而且其收缩力会进一步下降。

Difference analysis of left ventricular function in patient-s with different Child grading of liver cirrhosis using t-wo dimensional speckle tracking technique

Objective To analyze the left ventricular index differences of patients with cirrhosis by 2D speckle tracking technology. Methods 68 cases with cirrhosis in our hospital were randomly selected. According to Child classes, 68 cases were divided into A, B, C three grade groups, while 28 healthy subjects as a control group. With the application of 2D speckle tracking technology, all the patients were tested under the on-site operations. We obtained the highest value of systolic 16 horizontal, vertical directions and three-dimensional in left ventricular from three experiments and the control groups, we could analyse the differences of index between various Child classification of liver cirrhosis. Result The systolic pressure, diastolic pressure and pulse pressure of three cirrhosis groups were lower than the control group, but the heart rate were higher, which indicated the difference was statistically significant(P<0.05); In addition to the highest systolic value of apical side wall segment of left ventricular, the highest systolic values of the other cross-sections and longitudinal sections of three-dimensional directions from Child A, B, C three grade cirrhosis experiment groups were lower than the control group, which demonstrated the difference was statistically significant(P<0.05); After each pairwise comparison of the maximum systolic value of apical segment, intermediate segment and basal segment of left ventricular from three experiment groups, we found that the lowest level group was Child C while Child A was the highest, and the difference was statistically significant(P<0.05). Conclusion The part of the left ventricle in patients with cirrhosis had segmental contractility complications, and with the higher Child series(C level>B Level >A Level), more sections of left ventricular segments will reduce shrink force, and its contractile force will decline further.