准分子激光原位角膜磨镶术后角膜表面像差的变化

目的 评估激光原位角膜磨镶术（Lasik）术后近远期、正常角膜前后表面及全角膜像差的变 化。方法 选取1995 年1 月—2008 年12 月于西安市第四医院准分子激光中心行Lasik 手术的113 例患者作 为远期组，另选取2016 年4 月—2016 年5 月于西安市第四医院做视力检查的正常近视眼患者63 例作为对照 组，对照组行飞秒激光制瓣Lasik 后的患者作为近期组。测量各组角膜前后表面及全角膜像差，对比术后近远 期及未手术者前后表面和全角膜像差的变化。结果 远期组角膜前表面和全角膜球差、彗差、三叶草及总高 阶像差大于正常组和近期组（P <0.05），远期组角膜后表面彗差、三叶草及总高阶像差大于正常组和近期组 （P <0.05）。结论 Lasik 术后角膜前表面及全角膜像差较正常角膜高，并且术后远期角膜像差高于术后早期。 术后像差的增加与角膜瓣的制作、基质床的切削、激光参数及术后伤口愈合等有关。

The study of changes about the corneal aberration and surface aberration after Lasik surgery long-term and recent

Objective To evaluate the of corneal aberration and surface aberration among eyes after Lasik surgery for long or short term and normal eyes. Methods Patients undergoing the Lasik surgery from January 1995 to December 2008 were selected as long-term group, patients undergoing Lasik flapped with femtosecond laser 1 month ago were short-term group, and subjects with normal eyes were control group. Using Pentacam analytic system to measure the corneal aberrations and surface aberrations, and the data were compared among 3 groups. Results Compared with the control group and the short-term group, spherical aberration and coma aberration of anterior corneal surface and whole corneal surface, trefoil and whole aberration in the long-term group increased (P < 0.05). The value of posterior corneal surface coma aberration, trefoil and whole aberration in long-term group were higher than those in short-term and control group (P < 0.05). Conclusions The anterior surface and whole corneal aberration after Lasik surgery are higher than those of normal eyes, and the aberration of long-term group is higher than that of short-term group. The increased of aberration after surgery is related to the created of corneal flap, the ablation of corneal stromal bed, the parameters of laser and the wound healing after surgery.