心脏再生的研究新进展

心肌梗死后容易发生心衰、恶性心律失常甚至猝死等而威胁患者生命,有效改善心梗患者心功能促进心肌再生已经成为研究的热点。目前促进心肌再生的方法可大体概括为干细胞法诱导心肌增殖,微小核糖核酸诱导心肌再生,调控心肌细胞增殖有关的通路及细胞周期因子诱导心肌增殖,调节心肌细胞微环境诱导心肌增殖。虽然这些方法的研究都取得了一定的进展,但许多机制并未明确,也有诸多问题没有解决,还需要更深入的研究,随着心脏再生的研究,这一领域必将带来振奋人心的结果。

Recent advances in cardiac regeneration

Heart faliure , malignant arrhythmia ,and even sudden deathare more likely to occurred when a person was diagnosed with myocardial infarction,which seriously threatening the patient"s life, effectively improving heart function after myocardial infarction and promote heart regeneration have become a hot spot of research. The methods of promoting heart regeneration include stem cells induced hert regeneration, microRNAs induced hert regeneration, cell pathway and cell cycle regulatory factors induced hert regeneration ,and myocardial microenvironment induced hert regeneration. Although these methods have made some progress, but many mechanisms have not been clear, in-depth research is needed, with the constant study of heart regeneration, these studies would lead to exciting results