血栓抽吸对急性心肌梗死患者直接经皮冠状动脉介入术罪犯血管血流的影响

[摘要]【目的】 分析血栓抽吸对急性心肌梗死（AMI）患者直接经皮冠状动脉介入术（PPCI）罪犯血管血流的影响。【方法】 收集我院收治的90例行PPCI术的AMI患者的临床资料。按是否进行血栓抽吸分为对照组（单纯PPCI术,n=40）与研究组（血栓抽吸联合PPCI术,n=50）,比较两组临床治疗结果、罪犯血管血流变化及术后1周与术后远期不良心血管事件发生率。【结果】 ①术后,两组0-2级所占比例明显降低,与术前对比差异有统计学意义（P<0.05）,研究组术后0-2级所占比例明显低于对照组（P<0.05）。②研究组术后ST段回落良好所占比例为60.00%,略高于对照组,但对比差异无统计学意义（P>0.05）;研究组术后1周左室射血分数（LVEF）高于对照组,左室舒张末期内径（LVEDD）低于对照组（P<0.05）。③研究组术后1周不良时间发生率与对照组比较差异无统计学意义（P>0.05）,其随访远期总不良事件发生率略低于对照组,但比较差异无统计学意义（P>0.05）。【结论】 血栓抽吸可改善AMI患者PPCI术后罪犯血管血流灌注,改善患者左室功能,降低患者远期心血管不良事件发生率。

Effect of thrombus aspiration on culprit vessel blood flow in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention

[Abstract] [Objective] To analyze the effect of thrombus aspiration on culprit vessel blood flow in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PPCI). [Methods] The clinical data of 90 patients with AMI treated with PPCI in our hospital were collected. The patients were divided into the control group (simple PPCI, n=40) and the study group (thrombus aspiration combined with PPCI, n=50). The clinical treatment outcomes, changes of culprit vessel blood flow and the incidence of adverse cardiovascular events in 1 week and long-term after operation were compared between the two groups. [Results] After operation, the proportions of grade 0-2 in the two groups were significantly lower than those before operation (P<0.05), and the proportion in the study group was significantly lower than that in the control group (P<0.05). The excellent and good rate of ST segment fall in the study group (60.00%) was higher than that in the control group (P>0.05). The left ventricular ejection fraction (LVEF) of the study group was higher than that of the control group at 1 week after operation, and the left ventricular end diastolic diameter (LVEDD) was lower than that of the control group (P<0.05). There was no significant difference in the incidence of adverse cardiovascular events between the two groups at 1 week after operation (P>0.05), and the incidence rate in the long-term follow-up of the study group was slightly lower than that in the control group (P>0.05). [Conclusion] Thrombus aspiration can improve the culprit vessel blood perfusion of patients with AMI undergoing PPCI, improve the left ventricular function and reduce the incidence of adverse cardiovascular events in long term.