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毒邪在肝豆状核变性致病中的作用
引用本文:杨文明,张春海,李瑞娟,董婷,汪美霞,杨兴涛,鲍远程.毒邪在肝豆状核变性致病中的作用[J].中国实验方剂学杂志,2009,15(11):109-111.
作者姓名:杨文明  张春海  李瑞娟  董婷  汪美霞  杨兴涛  鲍远程
作者单位:安徽中医学院第一附属医院,安徽,合肥,230031
基金项目:安徽省科技攻关计划,国家中医药管理局科研项目,安徽省学科拔尖人才基金,重点学科基金 
摘    要:目的:目的:探讨毒邪在肝豆状核变性发病中的地位。方法:阐述传统医学及现代医学对毒邪的认识,毒邪对机体造成的损害,并重点阐述毒邪在肝豆状核变性致病中的作用。结果:毒邪是临床上常见的致病之邪,它可造成机体多方面的损害,肝豆状核变性是一全身性疾病,涉及多个系统、器官,铜浊毒邪内聚体内是其发病的病理生理学基础,也是从毒论治的依据所在。结论:毒邪在肝豆状核变性致病中起着十分重要的作用,铜毒内蓄,损伤肝络、脑络以及全身的络脉是肝豆状核变性的病机关键,从毒论治是肝豆状核变性的临床治疗的重要途径。

关 键 词:毒邪  肝豆状核变性  病机
收稿时间:2/1/2009 12:00:00 AM

Pathogenetic Role of Poison in Wilson's Disease
YANG Wen-ming,ZHANG Chun-hai,LI Rui-juan,DONG Ting,WANG Mei-xi,YANG Xing-tao,BAO Yuan-cheng.Pathogenetic Role of Poison in Wilson's Disease[J].China Journal of Experimental Traditional Medical Formulae,2009,15(11):109-111.
Authors:YANG Wen-ming  ZHANG Chun-hai  LI Rui-juan  DONG Ting  WANG Mei-xi  YANG Xing-tao  BAO Yuan-cheng
Abstract:Objective:To investigate the pathogenetic role of poison in wilson's disease.Methods: The understandings of poison from both Chinese traditional medicine and western medicine were collected,Damages to organism by poison,especially the pathogenetic role of poison in wilson's disease,were discussed.Results: Poison is a common pathogenetic factor clinically and may cause damage to many organs.Wilson's disease is a systemic disease which refers to multi-systems and organs,the accumulation of copper poison in the body is its pathophysiologic basis,and also the foundation of therapeutical method for disintoxicating.Conclusion: Poison plays a very important role in the pathogenetic factors for Wilson's disease.The key pathogenesis of Wilson's disease is the accumulation of copper poison in the body,and it cause the damage to the collaterals of liver,the collaterals of brain and the whole body's collaterals.The direct disintoxication is an important method of treating Wilson's disease.
Keywords:poison  hepatolenticular degeneration  pathogenesis
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